What We Do
What It Is
Rox is an oxygen delivery platform where oxygen is encapsulated in a nanoparticle or nanobubble. Rox delivers oxygen to retinal tissues in need when hypoxic conditions threaten the health of cells in the retinal layers. The technology is being developed to treat Central Retinal Artery Occlusion (CRAO), which is a stroke-like condition of the retina that leads to irreversible blindness. No therapy currently exists to treat this condition.
What it does
For the treatment of CRAO, nanobubbles are introduced into the eye by intravitreal injection. The nanobubbles then disperse through the vitreous and make their way to the retina. Here, the shells of the nanobubbles are denatured/disintegrated to release oxygen encapsulated at the core of the nanobubble, safely delivering oxygen to the surrounding tissue to revive the cells from hypoxia.
Who it is for
The Rox technology is currently focused on CRAO with potential future applications to treat other ocular ischemic conditions.